Всероссийский научно-исследовательский институт физиологии, биохимии и питания животных – филиал Федерального государственного бюджетного научного учреждения «Федеральный научный центр животноводства – ВИЖ имени академика Л.К. Эрнста»
1Galochkin V.A., 2Boryaev G.I., 1Agafonova A.V., 1Galochkina V.P.
1Institute of Animal Physiology, Biochemistry and Nutrition, Borovsk Kaluga oblast,
2Penza State Agrarian Academy, Penza, Russian Federation
ABSTRACT. The aim was to study efficacy of the lithium oxyglycinate to increase the stress resistance in pregnant sows and suckling piglets. The trial was performed on 2 groups of sows (n=4) and 4 groups of piglets (n=16). Sows of group I (control) after 1 mo after insemination were injected once i.m. a prolonged form of lithium oxyglicynate (LOG) at a dose of 2 mg/kg BW. The first (control) and second groups of piglets were taken from the sows of control group, in group II LOG was administered i.m. at 3-day age once at a dose of 2 mg/kg BW. Piglets of groups III and IV were taken from sows of experimental group, in group IV the piglets were injected once at the same dose as sows and piglets in group II. Blood samples were taken at the end of the experiment until weaning at 30 days of age. A single injection of LOG had no effect on fertility of sows and body weight of piglets at birth. Survival of piglets in groups II and IV was higher vs control (90 and 95% vs 76% in control, P = 0.06), and BW in these groups at the time of weaning was by 10 and 13% higher vs control group. Body weight of piglets in group III was 5% higher than the control, but lower than in piglets of groups II and IV. The blood plasma concentration of high density lipoprotein cholesterol in piglets of groups II and IV was higher than in the controls by 8 (P<0.1) and 17% (P<0.05), respectively. The ratio of contents of sulfhydryl and disulfide groups (SH/SS) in blood plasma was increased (P<0.05) in these groups. At 27 d after injection, the levels of adrenaline and noradrenaline in blood plasma in groups II and IV were reduced relative to control (for adrenaline by 3-4, P <0.05, by noradrenaline by 4-5 times, P<0.05). The data obtained suggest high efficiency of сombined use of injectable preparations of LOG in sows and piglets grown under them.
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