Всероссийский научно-исследовательский институт физиологии, биохимии и питания животных – филиал Федерального государственного бюджетного научного учреждения «Федеральный научный центр животноводства – ВИЖ имени академика Л.К. Эрнста»
The object was to study the action of recombinant probiotic strain of lactobacilli with growth hormone releasing factor gene on milk productivity in goats and cows. The trial I was performed on goats, preparation was given to 5 goats on 3rd mo of lactation daily during 6 weeks at the dose 25×109 CFU, 5 goats were control. In the trial II, recombinant probiotic was given to 8 cows on 4-5 mo of lactation daily during 2 mo at the dose 26×109 CFU (group I), non-recombinant strain was given to 8 cows at the same dose (group II), 8 cows were control group. In all trials, recombinant preparation stimulated milk formation and ameliorated feed efficiency. In the trial III, recombinant probiotic was given to 10 cows on 3-4 mo of lactation at the dose of 200×109 CFU (group I, n=10) or 1000×109 CFU (group II, n=10), 10 cows were control group. In goats received preparation, daily milk yield in the course of last 2-3 weeks was higher vs control by 26.5% (P<0.05). In the trial II in the course of last 5 weeks, milk yield in group I was higher by 10% (P< 0,05) vs group II and by 8,1% (P< 0,05) vs group III. In the trial III the daily milk yield in group I and II was higher by 6,3 and 13.2% vs control. In all trials, recombinant probiotic did not occur influence on milk fat and protein content. The data obtained suggest that the use of recombinant probiotics expressing somatoliberin may be a real alternative to methods of stimulating milk productivity based on the using injections of recombinant STH.
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