Всероссийский научно-исследовательский институт физиологии, биохимии и питания животных – филиал Федерального государственного бюджетного научного учреждения «Федеральный научный центр животноводства – ВИЖ имени академика Л.К. Эрнста»
ABSTRACT. The effect of an intracerebroventricular microinjection of cholecystokinin (CCK33, Sigma Aldrich,1 ng/g BW) on feeding and thermoregulatory behavior in goldfish Carassius auratus was investigated. It was shown that average daily selected temperatures (ST) increased significantly under the influence of CCK during two days of the experiment (up to 28.1±0.1°С), and further relative stabilization of ST value was observed until the end of the experiment. During all period of the observation, ST value in the fish of the experimental group was significantly lower than that in the fish of the control one. The maximal decreasing of ST was observed at the 8th day of experiment. CCK did not change locomotor feeding reactions, but significantly reduced the food intake in fish. After 1 h of the intracerebroventricular injection of CCK, the ration was reduced by 44% compared with the control. Under the influence of the intraperitoneal injection of CCK, the ration was reduced compared to the control fish after 5 h of the injection only, and compared to the intact fish – after 1 and 5 h (by 46.3 and 77.5% respectively). That is, CCK reduces the magnitude of ST and does not exert influence on fish locomotor feeding reaction, but significantly reduces food intake. The nature and effect of CCK and serotonin (5-HT) on thermoregulatory behavior and locomotor feeding reactions are different, and that of diet are similar. The data obtained suggest that these two neurotransmitters involve different systems in the regulation of feeding behavior of fish and their behavior in a thermally inhomogeneous medium.
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