Всероссийский научно-исследовательский институт физиологии, биохимии и питания животных – филиал Федерального государственного бюджетного научного учреждения «Федеральный научный центр животноводства – ВИЖ имени академика Л.К. Эрнста»
ABSTRACT. The effect of cholecystokinin (CCK) on the level of glycemia in 3 species of fish was studied: carp Cyprinus carpio L., roach Rutilus rutilus (L.), perch Perca fluviatilis L. All fish from the experimental group (5 specimens) at the same time day (10 hours) intraperitoneally injected cholecystokinin at a dose of 100 ng/kg body weight in Ringer's solution; In the control group, Ringer's solution was administered. In the first series of experiments, 1 h after injection of CCK fish (carp, roach and perch) was decapitated and blood was taken from the tail vessels. In the second series of experiments in carp, the effect of CCT on the dynamics of glycemia was investigated. The affects of intraperitoneal administration of CCK33 on the level of glycemia in fish of different species was established; after 1 hour after administration of CCK, the concentration of the blood glucose in perch increased by 19% (P<0.05), in roach it decreased by 17% (P<0.05), compared to the control. In carp, in both series of experiments, there was no significant change in the index after 1 h after the administration of the hormone. The dynamics of the level of glycemia in carp under the influence of CCK is an oscillatory character. There was a significant increase in the index during the first 3 hours of the experiment in comparison with intact fish, followed 24 hours later by a decrease to a minimum level after 72 hours, which with some fluctuations persists for 7 days. When compared with the control, a significant effect (P<.0.05) is noted in 0.5, 48, 120 and 168 h, while the stimulating effect of CCK predominates. It is suggested that an increase in the level of glycemia under the influence of CCK may enhance the inhibitory effect of the hormone on the food behavior of fish. The mechanisms of influence of CCK on the level of glycemia and the feeding behavior of fish are discussed.
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