Всероссийский научно-исследовательский институт физиологии, биохимии и питания животных – филиал Федерального государственного бюджетного научного учреждения «Федеральный научный центр животноводства – ВИЖ имени академика Л.К. Эрнста»
ABSTRACT. The effects of hormones, neurotransmitters and neuropeptides in the regulation of fish nutrition have been well studied, but the role of the nervous system has been studied to a lesser extent. The aim was to study the effect of adrenolytics acting on α-adrenoreceptors (aminazine) and β-adrenoreceptors (pindolol) on the rate of food reaction (latent feeding time, LFT) in carp Cyprinus carpio. Three groups of fish were formed.Aminazine or pindolol were injected intraperitoneally in experimental groups in doses of 1.0, 0.75, 0.5, 0.1, and 0.05 mg/g of body weight. Fish of the control group were injected with Ringer's solution. The latent feeding time of the group of fish (inversely proportional to the rate of the food reaction) was fixed immediately after the injection ("zero point"), and also 0.5 hours later and every 0.5 hours or 1 hour for 7 or 9 hours after the injection of the test substances. A total of 20 experiments were carried out. The introduction of both drugs caused a prolonged increase in LFT. With the introduction of aminazine at a dose of 1 mg/kg, the maximum increase in LFT (6-fold) was observed at 1 hour after injection, that of pindolol after 0.5 hours (2-fold). The return of LFT to normal in the first case occurred in 6 hours, in the second - after 8 hours. Smaller doses of drugs (0.75 and 0.5 mg/kg), as a rule, cause less effect. In the study of pindalol, a second increase in LFT was established after 4 hours. The observed differences are explained by the different mechanisms of action of the adrenolytics studied. Aminazine acts mainly on central α-adrenoreceptors, pindolol − on peripheral β-adrenoreceptors. It was suggested that different degrees of decrease in the rate of the food reaction with the administration of the drugs studied are due to the different roles of α- and β-adrenoceptors in the realization of the food-producing reaction of fish.
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