Всероссийский научно-исследовательский институт физиологии, биохимии и питания животных – филиал Федерального государственного бюджетного научного учреждения «Федеральный научный центр животноводства – ВИЖ имени академика Л.К. Эрнста»
1Galochkin V.A., 2Boryaev G.I., 2Zdorov’eva E.V., 1Galochkina V.P.
1Institute of Animal Physiology, Biochemistry and Nutrition, Borovsk, Kaluga oblast;
2Penza State Agrarian Academy, Penza, Russia
The trial was performed on 400 laying chickens, which were assign to 4 groups, 100 chickens each, fed during 41 days a basic diet supplemented with dihydroethoxyquin (DHE, 100 mg/kg of feed, group I) or selenopyran (SP, 12 mg/ kg of feed, group II). Two groups were control. At 25th day, the blood probes were taken (n=5) for biochemical investigation. In both treatment groups, content of high density lipoprotein cholesterol increased (P<0.001) and that of low density lipoprotein cholesterol decreased (P<0.001) vs control. Malonate dialdehyde content of yolk in control group was 10 times higher compared with blood. Malonate dialdehyde content of yolk in group I was 36% (P<0.001) and that in group II was 28% (P<0.001) of the control level. Egg productivity in groups I and II was higher by 5.8 (P<0.001) and 7.3% in comparison with control. Hatchability of chicks increased in group I by 14.6% (P<0.001) and in group II by 15.6% (P<0.001). There was concluded that water soluble (DHE) and fat soluble (SP) antioxidants exert approximately equal positive influence on biological functions and productivity traits in laying chickens.
Bailey C.A., Srinivasan L.J., McGeachin R.B.The effect of ethoxyquin on tissue peroxidation and immune status of single comb White Leghorn cockerels. Poult. Sci., 1996, 75(9): 1109-1120.
Bindoli A. Lipid peroxidation in mitochondria. Free Radical Biology & Medicine, 2005, 5: 247-261.
3. Galochkin V.A. Novye gorizonty povysheniya nespetsificheskoi rezistentnosti i produktivnosti zhivotnykh (New prospects in the increasing of animal's natural resistance). Borovsk, 2008, 97 p.
Galochkin V.A., Galochkina V.P. Problemy biologii productivnykh zhivotnykh - Problems of Productive Animal Biology, 2013, 2: 52-59.
5. Galochkin V.A., Cherepanov G.G. Problemy biologii productivnykh zhivotnykh - Problems of Productive Animal Biology., 2013, 1: 5-29.
Hansen T.K. Inhibitory effect of the antioxidant ethoxyquin on electron transport in the mitochondrial respiratory chain. Biochem. Pharmacol., 2001, 49(3): 283-289.
Issledovanie sinteticheskikh i prirodnykh antioksidantov in vitro i in vivo (metodicheskoe posobie) (Investigations of synthetic and natural antioxidants: a methodical manual). Moscow: Nauka, 1992, 197 p.
KarpishchenkoA.I. Meditsnskaya laboratornaya diagnostika. Programmy i algoritmy (Medical laboratory diagnostics: Programs and algorithms). St. Petersburg: Intermedika, 2001, 530 p.
Kim H.L. Effect of Santoquin on humoral immune function in mice: lack of interference with selenium utilization. Immunol. Cell. Biol., 1989, 67(1): 83-84.
Kim H.L. Accumulation of ethoxyquin in the tissue. J. Toxicol. Environ. Health., 1991, 33(2): 229-236.
Lauridsen C., Jakobsen K., The influence of dietary ethoxyquin on the vitamin E status in broilers. Poult. Sci., 1997, 76(7): 832-839
Middleton T.F., Ferket P.R., Boyd L.C. The effect of ethoxyquin on the quality of ground poultry mortality carcasses preserved by lactic acid fermentation and phosphoric acid stabilization. Poult. Sci., 2001, 80(8): 1154-1163.
Mysik A.T. Zootekhniya - Zootechnics, 2012, 1: 3-7.
Nazarenko G.I., Kishkun A.A. Klinicheskaya otsenka rezul'tatov laboratornykh issledovanii (Clinical assessment of of the laboratory analysis data). Moscow: Meditsina, 2002, 544 p.
Reyes J.L., Hernandez M.E., Melendez E., Gomez-Lojero C. Toxicosis in broiler chicks due to excess dietary ethoxyquin. Avian Dis., 1992, 36(4): 1102-1106
Wang S.Y., Bottje W., Maynard P., Dibner J., Shermer W. Effect of Santoquin and oxidized fat on liver and intestinal glutathione in broilers. Poult. Sci., 1997, 76(7): 961-967.